Archive for September 28, 2010

Larger amounts of Vitamin C (ascorbic acid) than the Recommended Daily Allowance are often required to maintain health and to combat infections such as the com­mon cold and influenza — in fact, any acute infection. It can be taken in different ways. Doses recommended by Linus Pauling are:—

1. Infants: 100 mg to 250 mg Daily

Freshly prepared orange juice has been the usual method of giving Vitamin C to babies, and is excellent. However, oranges differ so greatly with the time of year and the length of time since they were gathered, that they cannot be relied upon alone to supply sufficient Vitamin C for a child, especially if he has a cold or some other infection. Depending on the type of orange and time of year one fruit contains 40 mg to 55 mg Vitamin C.

The prepared orange juices, e.g., Nyal or Allenbury’s Orange Juice Compound give a standardized amount of Vitamin C per given dosage. However, some chil­dren are allergic to orange juice whilst others object to its taste.

Rose Hip or Blackcurrant Syrup is a most useful alternative to giving standardized Vitamin C. It usually contains about 15 mg per 5 ml. The natural syrup is also rich in other vitamins and minerals, and a sugarless formula is preferable.

2. Children: 500 mg Daily

This dosage is preferable taken as two flavored tablets — 250 mg strength — one morning and one evening.

Most flavored tablets are buffered, that is, part of the ascorbic acid of the tablet has been replaced by sodium ascorbate thus making the tablet less acid. This means that there is less gastric irritation and less of the associated side effects, e.g., diarrhoea or bladder irrita­tion manifested by frequency or burning urine.

Any of these side effects can be prevented by build­ing up the dose gradually and by taking smaller, more frequent doses before, during or after meals. 3.  Adults: 1000 mg Daily

The most common, convenient and also the cheapest way is to take a tablet, preferable flavored. These should be chewed or sucked before, during or after meals. Two 500 mg orange flavored tablets (one morning and one evening) will give excellent protec­tion under normal circumstances.

In the case of infection at least 8 tablets (4000 mg) daily should be taken in divided doses.

There are now some protein coated 500 mg tablets available, which are easy to swallow and do not cause gastric irritation as it is slowly released in the stomach. These new tablets are particularly suitable for patients with peptic ulcer — who need extra Vitamin C as a healing factor in their diet.

Vitamin C is also available in the form of effervescent tablets, either alone or with Vitamin B and calcium. One tablet is usually equivalent to 1000 mg.

Several brands of flavored, buffered Vitamin C granules are available, which, when mixed with water, make a pleasant drink favored by both children and adults. (One level teaspoonful is normally equivalent to 1000 mg.) When higher doses of Vitamin C are re­quired it simply means increasing the number of drinks taken during the day.

When a patient is too sick or a child too young to suck or swallow tablets, and needs large or very frequent doses of Vitamin C, Adelle Davis advises that 50 ordinary 500 mg tablets be crushed and dissolved in a breakfast cup of hot (not boiling) water (or blended in a ‘Vitamiser’).

This solution is sweetened with honey and kept refrig­erated in a glass screw top jar. It keeps well for several days without losing its potency. One teaspoon would approxi­mate to 500 mg of ascorbic acid.

The very large amounts of ascorbic acid introduced by

Dr Fred Klenner to combat virus and bacterial infections and to neutralize poisons, and recently used by Drs Ewan Cameron and Linus Pauling in the treatment of cancer, are best given as the non-acid salt of ascorbic acid — sodium ascorbate.

This is practically tasteless, is easily soluble in water and is now being used frequently whenever large doses — in grams rather than milligrams — are needed, or when in­travenous or intramuscular treatments are advisable — for example, in drug addiction and overdose, alcoholism and in virus infections or cancer.

The ascorbate powder is very effective in overcoming hay fever and allergies when the flavoring and color in the commercial tablets could in themselves cause an allergic reaction. It is very suitable for hyperactive children who can get very little Vitamin C in their restricted diet, and do not always like the acid taste of pure ascorbic acid.

Ascorbate can be dissolved in fruit juice or milk or other beverage. A small level teaspoon contains about 2 grams (2000 mg); one rounded ordinary teaspoon contains about 3 grams; one heaped teaspoon about 4 grams.

These are approximate measures only as teaspoons differ in size — but they are convenient measures for the householder. Exact amounts and solutions are, of course, used in intravenous injections and intramuscular injections.

For a small patient in whom it is difficult to give in­travenous injections or when a doctor is not available — two to four grams can be given intramuscularly — in divided doses in different areas, the buttocks being the most con­venient.

Any pain of the I.M. injection can be prevented by applying ice to the area for several minutes before and again after the injection.

15 gm of sodium ascorbate sterilized with 0.5 ml of ethanol are now available from Oakleigh Laboratories, Regan Street, Mentone, Melbourne, for intravenous injec­tion. The usual dilution is 15 mg in 100 ml of distilled water, normal saline, Hartmen or Ringers Solution.
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There is, however, a totally new concept growing up as to the optimum daily amount of ascorbic acid or its salt, sodium ascorbate, necessary to keep the body saturated with the vitamin and able to withstand all the infections, pollution and degenerative diseases that seem to be the common lot of humans today. It is based on the amount of ascorbic acid naturally made by other animals who have the power to manufacture enough ascorbic acid for their own needs.

A growing group of medical men, bio-chemists and nutritionists advocate a gram a day for each year of age up to 10 years – and 10 grams daily thereafter into adult life. During any great stress even this dose is raised to 15 to 20 grams and, what is more, no serious side effects are reported.

This dosage is based on the amount of ascorbic acid manufactured naturally by other animals — mammals — per kilo body weight under normal conditions and during periods of stress. For example, a healthy goat weighing 70 kg — the size of an average man — is estimated to produce 13 grams of ascorbic acid a day in his liver.

The recommended dosage of Vitamin C is, of course, only average.

It must be remembered that each individual has his own special needs as regards each vitamin — Vitamin C included; and it is estimated that 10 to 15 percent of people differ from the average as to an optimum intake.

The availability of the non-acid salt of ascorbic acid, sodium ascorbate (or calcium ascorbate) crakes it easier to take high doses of Vitamin C without irritating the mouth, stomach or intestines or bladder as the straight ascorbic acid is inclined to do in some individuals.

A level small teaspoon of sodium ascorbate powder is estimated to equal 2 grams of Vitamin C, a rounded tea­spoon ’3 grams and a heaped teaspoon averages approx­imately 4 grams. It has little taste and can be conveniently dissolved in water, fruit juice, milk or any beverage.
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